KIM Hie Lim

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KIM Hie Lim

Assistant Professor
Phone: 
+(65) 65923078
Office Location: 
N2-01c-52
Education: 
  • PhD The Graduate Univ for Advanced Studies 2008
  • BSc Ewha Womans University 2003
Biography: 

Asst. Prof. Kim’s specialises in population genomic analyses, applied to genetic variations found within or between populations in order to infer the demographic history of the populations. During her PhD training in Japan, she studied population genetics and evolutionary biology. When she was a postdoctoral researcher at Penn State University, her research extended to Genomics and she applied population genetic analyses to whole genome sequence data. She joined ASE, NTU as a faculty member 2016. 

Research Interests: 

Asst. Prof. Kim’s current research projects are:

  • Studies on human population history related to environmental changes using whole genome population data in collaboration with the GenomeAsia 100K project (https://genomeasia100k.org/)
  • Evolution of human immune genes as a result of adaptation against infectious disease
  • Comparative genomics on air-born microbes
  • Population genetics on sea turtles nesting in Southeast Asia
Selected Publications: 
  • Wall JD, Ratan A, Swawiski E, Kim HL, Kim C, Gupta R, Suryamohan K, Gusareva ES, Purbojati RW, Bhangale T, Stepanov V, Kharkov V, Schrӧder MS, Ramprasad V, Tom J, Durinck S, Bei Q, Li J, Guillory J, Phalke S, Basu A, Stinson J, Nair S, Malaichamy S, Biswas NK, Chambers JC, Cheng KC, George JT, Khor SS, Kim JI, Cho B, Menon R, Sattibabu T, Bassi A, Deshmukh M, Verma A, Gopalan V, Shin JY, Pratapneni M, Santhosh S, Tokunaga K, Md-Zain BM, Chan KG, Parani M, Natarajan P, Hauser M, Allingham RR, Santiago-Turla C, Ghosh A, Gadde SGK, Fuchsberger C, Forer L, Shoenherr S, Sudoyo H, Lansing JS, Friedlaender J, Koki G, Cox MP, Hammer M, Karafet T, Ang KC, Mehdi SQ, Radha V, Mohan V, Majumder PP, Seshagiri S, Seo JS, Schuster S, Peterson AS. Identification of African-Specific Admixture between Modern and Archaic Humans, AJHG, Vol. 105, pp. 1254-1261, 2019.
  • Wall JD, Stawiski EW, Ratan A, Kim HL, Kim C, Gupta R, Suryamohan K, Gusareva ES, Purbojati RW, Bhangale T, Stepanov V, Kharkov V, Schröder MS, Ramprasad V, Tom J, Durinck S, Bei Q, Li J, Guillory J, Phalke S, Basu A, Stinson J, Nair S, Malaichamy S, Biswas NK, Chambers JC, Cheng KC, George JT, Khor SS, Kim JI, Cho B, Menon R, Sattibabu T, Bassi A, Deshmukh M, Verma A, Gopalan V, Shin JY, Pratapneni M, Santhosh S, Tokunaga K, Md-Zain BM, Chan KG, Parani M, Natarajan P, Hauser M, Allingham RR, Santiago-Turla C, Ghosh A, Gadde SGK, Fuchsberger C, Forer L, Schoenherr S, Sudoyo H, Lansing JS, Friedlaender J, Koki G, Cox MP, Hammer M, Karafet T, Ang KC, Mehdi SQ, Radha V, Mohan V, Majumder PP, Seshagiri S, Seo JS, Schuster SC, Peterson AS. The GenomeAsia 100K Project enables genetic discoveries across Asia. Nature, Vol. 576, pp. 106-111, 2019.
  • Gusareva ES, Acerbi E, Lau KJX, Luhung I, Premkrishnan BNV, Kolundžija S, Purbojati RW, Wong A, Houghton JNI, Miller D, Gaultier NE, Heinle CE, Clare ME, Vettath VK, Kee C, Lim SBY, Chénard C, Phung WJ, Kushwaha KK, Nee AP, Putra A, Panicker D, Yanqing K, Hwee YZ, Lohar SR, Kuwata M, Kim HL, Yang L, Uchida A, Drautz-Moses DI, Junqueira ACM, Schuster SC. Microbial communities in the tropical air ecosystem follow a precise diel cycle, PNAS, Vol. 12, pp. 23299-23308, 2019.
  • Yoo SK, Kim CU, Kim HL, Kim S, Shin JY, Kim N, Yang JSW, Lo WQ, Cho B, Matsuda F, Schuster SC, Kim C, Kim JI, and Seo JS, NARD: whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants, Genome medicine, Vol. 11, pp. 1-10, 2019.
  • Kim HL., Ratan A., Perry GH., Montenegro A., Miller W., and Schuster SC. 2014. Khoisan hunter-gatherers have been the largest population throughout most of modern human demographic history, Nature Communications, 5:5692, 2014.
  • Kim HL., Schuster SC. Poor man’s 1000 genome project: recent human population expansion confounds the detection of disease alleles in 7,098 complete mitochondrial genomes, Frontiers in Genetics, Vol. 4, Article 13. 2013.
  • Gupta R., Ratan A., Rajesh C., Chen R., Kim HL., Burhans R., Miller W., Santhosh S., Davuluri RV., Butte AJ., et al. Sequencing and analysis of a South Asian-Indian personal genome, BMC Genomics, Vol. 13, 440. 2012.
  • Miller W., Schuster SC., Welch AJ., Ratan A., Bedoya-Reina OC., Zhao F., Kim HL., Burhans RC., Drautz DI., Wittekindt NE., et al. Polar and brown bear genomes reveal ancient admixture and demographic footprints of past climate change, Proc. Natl. Acad. Sci. USA., Vol 109. E2382-E2390. 2012.
  • Kim HL., Igawa T., Kawashima A., Satta Y., and Takahata N., Divergence, demography and gene loss along the Human lineage, Phil. Trans. R. Soc. B., Vol. 365, pp. 2451-2457, 2010.
  • Kim HL. and Satta Y., Population genetic analysis of the N-Acylsphingosine Amidohydrolase gene associated with mental activity in Humans, Genetics, Vol. 178, pp.1505-1515, March, 2008.
Teaching: 

ES2301 Principles of Heredity and Ecological Genetics